Boosting Nitric Oxide for Better Energy, Stamina, and Hormonal Balance

Roma Kunde
Roma Kunde
March 10, 2025
10
min read
Technically reviewed by: 
Charisse Cartin
Boosting Nitric Oxide for Better Energy, Stamina, and Hormonal Balance
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Inside This Blog:

  • Introduction
  • Does Nitric Oxide Help Sexually?
  • Does Nitric Oxide Increase Testosterone?
  • Does Nitric Oxide Help with Erectile Dysfunction?
  • How to Increase Nitric Oxide in the Body

Do you often feel drained or low on energy? The secret to stamina, endurance, and hormone regulation might be hiding in your body in the form of nitric oxide (NO). This tiny but powerful molecule boosts circulation, helping deliver oxygen and nutrients throughout the body.

NO is commonly associated with heart health, but it also supports vitality in both men and women, influencing everything from workout performance to overall well-being [1]. Let’s explore how NO supports energy, strength, and hormonal balance, along with natural ways to boost its levels in the body.

Does Nitric Oxide Help Sexually?

Sexual wellness relies on hormonal balance and healthy blood flow, both of which NO helps regulate. This natural molecule helps relax blood vessels and improve circulation, supporting a healthy, active lifestyle.

NO is well known for supporting men’s sexual health by increasing energy levels, boosting testosterone, and enhancing libido. But NO isn’t just for men — its benefits also extend to women. NO helps regulate signaling molecules that influence mood, metabolism, and strength, contributing to hormonal balance [1 - 4].

For men and women, proper blood flow is essential for arousal, sensitivity, and sexual vitality. NO supports this process by ensuring that oxygen and nutrients reach the tissues. By enhancing circulation, NO helps sustain energy levels and responsiveness, both crucial for a healthy libido [1 - 4].

Did You Know? Beyond supporting circulation, NO fuels cellular energy by improving oxygen delivery and activating mitochondria — the powerhouses that generate energy in your cells. This process boosts stamina, reduces fatigue, and enhances overall body function, positively impacting sexual health [2, 5].

Does Nitric Oxide Increase Testosterone?

Testosterone is the male sexual hormone that regulates energy, muscle strength, and vitality. But did you know nitric oxide (NO) helps support its production? While NO itself doesn’t create testosterone, it improves the conditions needed for the body to produce and regulate this vital hormone.

NO supports testosterone production by enhancing blood flow and oxygen delivery to the testes, where the hormone is produced. Better circulation means these tissues receive all the nutrients and oxygen they need to function properly. Studies conducted in rats also suggest that NO stimulates chemicals that signal Leydig cells in the testes to produce testosterone [2, 4]. However, human studies are required to confirm these findings.

Nitric oxide supports testosterone production by improving blood flow and oxygen delivery to the testes, creating optimal conditions for hormone regulation.

Does Nitric Oxide Help with Erectile Dysfunction?

Treatment for erectile dysfunction often includes medications that enhance NO's effects.

As a signaling molecule, NO can help reverse the condition by triggering vasodilation or the widening of blood vessels. This process improves blood flow and oxygen delivery to penile tissues. When NO levels are low, circulation gets compromised, leading to weakened blood vessels and reduced energy levels [1-2, 4].

Besides improving circulation, NO helps protect blood vessels by reducing oxidative stress caused by harmful free radicals [2, 4]. It also enhances nerve function, improving communication between the brain and sexual organs [1]. Additionally, NO supports mitochondrial activity for efficient energy production, aiding muscle recovery and regulating key hormones like testosterone [2, 5].

By enhancing blood flow and reducing oxidative stress, NO helps combat erectile dysfunction [6-7]. Maintaining healthy NO levels can help your body function more efficiently, promoting sexual well-being and vitality. The good news is that you can do this through simple lifestyle changes like eating better and exercising.

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How to Increase Nitric Oxide in the Body

Your body naturally produces NO, but lifestyle choices can significantly impact how much of it your body generates. Here are some of the best ways to boost NO levels:

1. Eat NO-boosting foods

With the right nutrients, your body can naturally increase NO levels. Leafy greens like spinach, kale, and arugula and vegetables like beetroot and radish are rich in nitrates. Your body converts these nitrates into NO [8].

Citrus fruits such as oranges and lemons provide vitamin C, which helps stabilize and preserve NO levels. Superfoods like berries and nuts are packed with antioxidants that protect NO from breaking down too quickly, ensuring its benefits last longer [9].

2. Get moving

Physical activity effectively boosts NO by improving circulation and oxygen delivery, which stimulates NO production. Aerobic exercises like running, cycling, and swimming strengthen your blood vessels and support heart health. Resistance training, such as weightlifting and bodyweight exercises, enhances muscle function and endurance. Combining these exercises can help maximize NO levels and boost energy [10-11].

3. Try breathing exercises

Deep breathing techniques like nasal breathing stimulate NO production in the sinuses, improving oxygen uptake and circulation. Practices like diaphragmatic breathing, humming while breathing, alternate nostril breathing, and mindful breathwork enhance relaxation and lower stress. This contributes to healthier NO levels [12-13].

4. Consider supplements

Certain supplements, like the amino acids L-arginine and L-citrulline, help your body generate NO. Beetroot extract is another excellent option, as it provides a concentrated source of nitrates that can be converted to NO. Adding these supplements to your diet can provide an extra boost, especially if you have low NO levels [3], [4, 8, 14].

Making these small yet powerful changes can naturally boost NO levels, enhancing energy, stamina, sexual health, and overall well-being.

Final Thoughts

Whether you’re looking to improve endurance, sexual health, or long-term well-being, optimizing NO levels can be a smart and effective strategy.
Ready to check your nitric oxide levels? Diagnox’s Nitric Oxide Saliva Test Strips make it easy to monitor your NO levels anytime, anywhere. With a simple, at-home test, you can gain valuable insights into your body’s nitric oxide status—helping you make informed choices for better circulation, endurance, and overall health. Take the guesswork out of your wellness journey and start optimizing your nitric oxide levels today!

FAQs

Can stress impact nitric oxide levels?

Chronic stress can negatively affect nitric oxide production by increasing oxidative stress and inflammation, which can hinder blood flow and overall health.

What are the signs of low nitric oxide levels?

If you have low nitric oxide levels, you may experience fatigue, reduced endurance, poor circulation, and decreased sexual function.

Can diet alone effectively increase nitric oxide levels?

Diet plays a crucial role in maintaining nitric oxide levels. However, for the best results, it should be combined with regular exercise and natural supplements. This holistic approach helps sustain optimal nitric oxide levels over the long term.

How does L-arginine help boost sexual health?

L-arginine is a nitric oxide-boosting amino acid that enhances blood flow, which may help improve desire and arousal in women. Studies suggest it is a promising natural option with minimal side effects.

Are there any risks associated with nitric oxide supplements?

Nitric oxide supplements are generally safe for most people, but excessive intake may lead to side effects such as abdominal discomfort or blood pressure changes. It's important to consult a healthcare professional before starting any new supplement.

References

[1] M. R. Melis and A. Argiolas, “Erectile Function and Sexual Behavior: A Review of the Role of Nitric Oxide in the Central Nervous System,” Biomolecules, vol. 11, pp. 1866, Dec 2021.

[2] S. Dutta and P. Sengupta, “The Role of Nitric Oxide on Male and Female Reproduction,” Malays. J. Med. Sci., vol. 29, pp. 18-30, April 2022.

[3] N. E. Cieri-Hutcherson, A. Jaenecke, A. Bahia, D. Lucas, A. Oluloro, L. Stimmel, and T. C. Hutcherson, “Systematic Review of l-Arginine for the Treatment of Hypoactive Sexual Desire Disorder and Related Conditions in Women,” Pharmacy (Basel), vol. 9, pp. 71, March 2021.

[4] Y. Luo, Y. Zhu, W. Basang, X. Wang, C. Li, and X. Zhou, “Roles of Nitric Oxide in the Regulation of Reproduction: A Review,” Front. Endocrinol. (Lausanne), vol. 12, pp. 752410, Nov 2021.

[5] J. D. Allen, “Nitric oxide as a mediator of exercise performance: NO pain NO gain,” Nitric Oxide, vol. 136-137, pp. 8-11, July 2023.

[6] Mayo Clinic Staff, “Erectile Dysfunction: Overview,” Mayo Clinic, Available Online. [Accessed Feb 13, 2025].

[7] Mayo Clinic Staff, “Erectile Dysfunction: Diagnosis,” Mayo Clinic, Available Online. [Accessed Feb 13, 2025].

[8] D. Dos Santos Baião, D. Vieira Teixeira da Silva, and V. Margaret Flosi Paschoalin, “A Narrative Review on Dietary Strategies to Provide Nitric Oxide as a Non-Drug Cardiovascular Disease Therapy: Beetroot Formulations-A Smart Nutritional Intervention,” Foods., vol. 10, pp. 859, April 2021.

[9] H. Tkaczenko and N Kurhaluk, “Antioxidant-Rich Functional Foods and Exercise: Unlocking Metabolic Health Through Nrf2 and Related Pathways,” Int. J. Mol. Sci., vol. 26, pp. 1098, Jan 2025.

[10] O. Oral, “Nitric oxide and its role in exercise physiology,” J. Sports Med. Phys. Fitness, vol. 61, pp. 1208-1211, Sep 2021.

[11] O. M. Shannon, T. Clifford, D. R. Seals, D. H. Craighead, and M. J. Rossman, “Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes,” Nitric Oxide, vol. 125-126, pp. 31-39, Aug 2022.

[12] K. Abishek, S. S. Bakshi, and A. B. Bhavanani, “The Efficacy of Yogic Breathing Exercise Bhramari Pranayama in Relieving Symptoms of Chronic Rhinosinusitis,” Int. J. Yoga, vol. 12, pp. 120-123, May-Aug 2019.

About the Author
Roma Kunde

Roma Kunde is a freelance content writer with a biotechnology and medical background. She has completed her B. Tech in Biotechnology and has a certificate in Clinical Research. She has 6 years of writing and editing experience in fields such as biomedical research, food/lifestyle, website content, marketing, and NGO services. She has written blog articles for websites related to construction chemicals, current affairs, marketing, medicine, and cosmetics.

About the Reviewer
This blog was
Technically reviewed by: 
Charisse Cartin

Charisse Cartin is a talented and dedicated editor who has contributed significantly to this blog.

The blog was also reviewed by the Diagnox content team. Diagnox Staff consists of a multidisciplinary team of scientists, content writers, and healthcare professionals with an expertise to create and review high-quality, informative, accurate, and easy-to-understand content for both professionals and everyday readers. Our staff follows strict guidelines to ensure the credibility and authenticity of the information, reviewing them independently and verifying them by various scientific and technical sources to ensure accuracy. Our review team believes in delivering knowledge free from bias to improve public health and well-being.

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