Interpretation of Urine Test Strip Results
At-home dipstick tests can be used by both vets and pet owners to check ten different parameters in an animal’s urine. These commonly tested urine parameters include Leukocytes, Nitrite, Urobilinogen, Protein, pH, Blood, Ketone, Specific Gravity, Bilirubin, and Glucose. These urine parameters can provide a wealth of information about your pet’s health as well as help diagnose a broad spectrum of diseases.
Leukocytes
This test reveals the presence of Leukocytes esterase, generally referred to as white blood cells. These cells of the immune system protect the body against infections and pathogenic foreign bodies. A few white blood cells are not a cause of concern and yield negative or trace results. A positive test for leukocytes, or white blood cells, in the urine of cats and dogs, typically suggests an infection or inflammation in the urinary tract.
It is essential to note that the presence of leukocytes in the urine does not always indicate an infection or other problem in the urinary tract, as many factors can influence the results of a urinalysis. Therefore, a thorough evaluation by a veterinarian is necessary to determine the underlying cause of the leukocytes to prescribe appropriate treatment.
Nitrites
The occurrence of nitrites in the urine of cats and dogs usually indicates a bacterial urinary tract infection. Nitrites are formed in the urine when bacteria convert nitrate to nitrite as part of their metabolic process.
The presence of nitrites may prompt further diagnostic tests, such as a urine culture, to identify the specific bacteria responsible for causing the infection and determine the most appropriate treatment. Antibiotics are often used to treat bacterial urinary tract infections.
Urobilinogen
Urobilinogen is formed from the reduction of bilirubin, which is a yellowish substance found in the liver that helps break down red blood cells. Elevated levels of urobilinogen in the urine of cats and dogs can indicate various conditions, including liver disease, hemolytic anemia, and some forms of bacterial infections.
Protein
The occurrence of protein in the urine, also known as proteinuria, can indicate a variety of conditions, ranging from benign to serious. Protein is not normally found in the urine; however, occasionally, a small quantity of protein in urine is not considered clinically critical. If there is a kidney problem, protein can leak into the urine repeatedly, which requires medical attention.
The urine dipstick test is highly sensitive to albumin but can give false positives due to contaminants and the presence of cauxin in feline urine.
pH
The pH of urine refers to the level of acidity or alkalinity in the urine. The significance of urine pH in pet cats, dogs, and other animals can vary depending on several factors, such as diet and health conditions.
The normal pH range for urine in cats and dogs is between 6.0 and 7.5. A single urine pH reading is insufficient to diagnose a disease or condition. Combined with other parameters, a urine pH consistently outside the normal range helps identify possible factors that can cause metabolic, renal, gastrointestinal, or respiratory disorders.
Blood
The presence of blood in the urine is known as hematuria. Acute episodes of blood in urine could be due to muscle injury or trauma. However, chronic hematuria suggests an underlying medical condition requiring further evaluation and treatment.
Hematuria can be caused by various conditions, including urinary tract infections, bladder or kidney stones, urinary tract tumors, trauma or injury to the urinary tract, or due to certain systemic diseases such as kidney disease.
Specific Gravity
Urine Specific Gravity (USG) measures the concentration of all chemical particles in the urine. It determines the body’s hydration levels and the kidney’s ability to concentrate urine.
While USG in animals can have a broad normal range, USG is typically between 1.015 to 1.045 in healthy hydrated dogs and 1.035 to 1.060 in cats. USG consistently below this range may indicate underlying medical conditions such as diabetes insipidus, kidney disease, or overhydration. On the other hand, a specific gravity that is consistently above this range may indicate dehydration, kidney disease, or other conditions that cause the body to retain fluids.
Ketones
Ketones are produced when the body breaks down fat for energy instead of glucose. This can occur due to a carb-restrictive diet or when there is a shortage of glucose in the body.
Ketones are normally not present at detectable levels in the urine of cats or dogs. A positive ketone in urine test could be due to metabolic ketosis, electrolyte imbalances, diabetes mellitus, or prolonged hunger.
Bilirubin
Bilirubin is a chemical produced in the liver and normally excreted in the bile.
In healthy cats, bilirubin in urine is not present. However, in healthy dogs, trace to small quantities of bilirubin in urine is normal. Unusually high levels of bilirubin in the urine are associated with liver disease or red blood cell destruction (hemolysis) and should always be investigated by a veterinarian.
Glucose
In healthy cats and dogs, glucose is usually filtered out by the kidneys and reabsorbed into the bloodstream. However, if the glucose levels in the blood become too high, the kidneys may not be able to reabsorb all of the glucose, leading to glucosuria (i.e., glucose in the urine). It is mostly due to kidney disorders, such as diabetes mellitus. Glucosuria makes conditions ideal for bacterial growth and can cause urinary tract infections.
The Value of a Urinalysis
A urinalysis is a simple, inexpensive test that can help detect kidney diseases and other disorders. Since pets can't communicate how they're feeling and many conditions do not produce symptoms, regular urine examinations can identify important diseases before irreversible damage occurs. Urinalysis can also assess your pet's response to treatment and detect relapses.
You can perform a urinalysis at home using pet urine test strips and report any abnormal results to your vet.