UTI Testing - Why Does It Matter?

Dr. Mara Holton and Kathleen Mackey
Dr. Mara Holton and Kathleen Mackey
December 12, 2022
3
min read
UTI Testing - Why Does It Matter?
Listen to this article

If you've ever had a painful and uncomfortable Urinary Tract Infection (UTI), you understand how disruptive they can be. But why is testing so important when it comes to UTIs? The simple answer: it ensures you get the right treatment. Unlike other common infections, like sinus or respiratory infections that can sometimes be treated based on symptoms alone, UTIs require more specific testing to identify the exact cause [5]. Misdiagnosing or mistreating a UTI can lead to more serious health problems like kidney infections or antibiotic resistance.

Why does UTI testing matter?

  • Accurate Diagnosis - Symptoms like frequent urination, burning sensations, and abdominal pain can be caused by other conditions, such as bladder infections, kidney stones, or even STIs. Without proper testing, a UTI might be confused with another health issue, leading to delayed or incorrect treatment.
  • Choosing the Right Treatment - Not all UTIs are caused by the same bacteria. Testing helps identify the specific bacteria causing the infection, so doctors can prescribe the most effective antibiotic. Without testing, you might receive antibiotics that don’t work for your infection, which could allow it to worsen.
  • Prevents Antibiotic Resistance -  Taking the wrong antibiotic—or taking one when you don’t need it—can contribute to antibiotic resistance, making future infections harder to treat. Proper testing helps ensure antibiotics are used correctly.
  • Reducing Infection Recurrence -  Some people suffer from recurrent UTIs. Testing helps identify the underlying cause of frequent infections and guides long-term treatment strategies to help prevent them from coming back.

Diagnosis of UTI

There are three commonly used tests for diagnosing a UTI:

  • Dipstick Urinalysis
  • Urine Culture
  • Urine PCR (Polymerase Chain Reaction)

Dipstick Urinalysis

This test checks for signs of infection by detecting blood, nitrites, or white blood cells in your urine. However, it does not detect specific bacteria that cause UTIs.

  • The presence of these cells may suggest an infection, but they could also be caused by other issues like kidney stones, vaginal contamination, or even urologic cancers.
  • False positives are common, which can lead to unnecessary antibiotic use or missed diagnoses of other conditions.
A urine dipstick test for UTIs is a fast and easy way to check for infection by looking for signs like bacteria and white blood cells in the urine.

Urine culture

This is often referred to as the "gold standard" for UTI testing, but it’s not perfect.

  • It only detects about 73% of UTIs, meaning over 25% of patients with a UTI may get a negative result. In these cases, the infection could go untreated.
  • If multiple organisms are present, the test may not identify all of them.
  • It can take anywhere from 2 to 10 days to get the results, which delays treatment.
A urine culture is a lab test that grows bacteria from a urine sample to identify if there's an infection and determine the best antibiotic for treatment.

Urine PCR

This is a more advanced test that’s highly accurate because it amplifies bacterial DNA in the urine.

  • You can get results in as little as 6 to 8 hours once the sample reaches the lab.
  • However, it only tests for specific organisms on a panel, so healthcare providers must use their clinical judgment when interpreting results.
  • It can also identify genes that make bacteria resistant to antibiotics, helping doctors choose the most effective treatment.
A urine PCR test checks for bacteria in a urine sample by looking for their DNA, helping to quickly and accurately diagnose infections.

Why Accurate Testing is Important

While dipsticks, at-home testing strips, and questionnaires can help figure out whether your symptoms are due to a UTI or STI, definitive testing is key to identifying the exact cause. This allows your healthcare provider to select the right antibiotic or therapy, avoiding unnecessary treatments and helping you recover faster. Working with a healthcare provider who understands the pros and cons of each test is crucial for getting the right care!

Clear information is the most valuable resource you can have on your side.
Stay in the loop!
Thank you for subscribing. Stay informed, stay healthy!
Oops! There was a problem with your submission. Please check your email address and try again.

About the Authors:

Dr. Mara Holton and Kathleen Mackey first met in 2007 while practicing general urology with a large local urology group.  At the time, Dr. Holton had just recently completed her urologic residency at the University of Maryland, and Kathleen had been in practice with the group as a CRNP for just over a year.  

Although both practiced general urology, over the years, the majority of their patient population became women experiencing recurrent urinary tract infections, urinary incontinence, uncomfortable vaginal symptoms, and difficulty with sexual activity.  They quickly found a common theme that many women had experienced these symptoms for years prior to identifying a provider who could address their concerns.  Unfortunately, many patients recounted that, when they did seek help, they were often undertreated, misdiagnosed, or led to believe their symptoms were just something that had to be tolerated. Many women described scenarios of being brushed off by male providers or told that their symptoms were a normal part of aging. As active women and mothers themselves, Mara & Kathleen empathized with the burden these conditions caused and the associated negative impacts on the quality and enjoyment of life.  In developing Snippa, a female-focused health care platform,  Mara and Kathleen seek to broaden and expand their reach and efforts in order to educate patients about pelvic health and to advocate for access to care, research into , and the development of treatment alternatives for these prevalent health conditions.

References

[1] Ahmed, S., Alsalloom, A, Babikir, I., Alhoumoud, B. (2019). Uropathogens and their antimicrobialvpatterns: Relationship with urinary tract infections. International Journal of Health Sciences. 2019 Mar-Apr; 12 (2): 48-55.

[2] Chua, K.-P., Fischer, M. A., & Linder, J. A. (2019). Appropriateness of outpatient antibiotic prescribing among privately insured US patients: ICD-10-CM based Cross Sectional Study. BMJ.

[3] Davenport M, Mach KE, Shortliffe LMD, Banaei N, Wang TH, Liao JC. New and developing diagnostic technologies for urinary tract infections. Nat Rev Urol. 2017;14(5):296-310.

[4] García LT, Cristancho LM, Vera EP, Begambre O. A New Multiplex-PCR for Urinary Tract Pathogen Detection Using Primer Design Based on an Evolutionary Computation Method. J Microbiol Biotechnol. 2015 Oct;25(10):1714-27.

[5] LaMotte, S. (2021, February 24). Doctors treat female UTIs with wrong antibiotics nearly half the time, study finds. CNN. Retrieved Dec 11, 2022.

[6] Mambatta, A. K., Jayarajan, J., Rashme, V. L., Harini, S., Menon, S., & Kuppusamy, J. (2015). Reliability of dipstick assay in predicting urinary tract infection. Journal of family medicine and primary care, 4(2), 265–268.

About the Author
Dr. Mara Holton and Kathleen Mackey

Dr. Mara Holton and Kathleen Mackey first met in 2007 while practicing general urology with a large local urology group.  At the time, Dr. Holton had just recently completed her urologic residency at the University of Maryland, and Kathleen had been in practice with the group as a CRNP for just over a year.  

Although both practiced general urology, over the years, the majority of their patient population became women experiencing recurrent urinary tract infections, urinary incontinence, uncomfortable vaginal symptoms, and difficulty with sexual activity.  They quickly found a common theme that many women had experienced these symptoms for years prior to identifying a provider who could address their concerns.  Unfortunately, many patients recounted that, when they did seek help, they were often undertreated, misdiagnosed, or led to believe their symptoms were just something that had to be tolerated. Many women described scenarios of being brushed off by male providers or told that their symptoms were a normal part of aging. As active women and mothers themselves, Mara & Kathleen empathized with the burden these conditions caused and the associated negative impacts on the quality and enjoyment of life.  In developing Snippa, a female-focused health care platform,  Mara and Kathleen seek to broaden and expand their reach and efforts in order to educate patients about pelvic health and to advocate for access to care, research into , and the development of treatment alternatives for these prevalent health conditions.

About the Reviewer
This blog was
Medically reviewed by:
Dr. Mara Holton and Kathleen Mackey

Dr. Mara Holton and Kathleen Mackey first met in 2007 while practicing general urology with a large local urology group.  At the time, Dr. Holton had just recently completed her urologic residency at the University of Maryland, and Kathleen had been in practice with the group as a CRNP for just over a year.  

Although both practiced general urology, over the years, the majority of their patient population became women experiencing recurrent urinary tract infections, urinary incontinence, uncomfortable vaginal symptoms, and difficulty with sexual activity.  They quickly found a common theme that many women had experienced these symptoms for years prior to identifying a provider who could address their concerns.  Unfortunately, many patients recounted that, when they did seek help, they were often undertreated, misdiagnosed, or led to believe their symptoms were just something that had to be tolerated. Many women described scenarios of being brushed off by male providers or told that their symptoms were a normal part of aging. As active women and mothers themselves, Mara & Kathleen empathized with the burden these conditions caused and the associated negative impacts on the quality and enjoyment of life.  In developing Snippa, a female-focused health care platform,  Mara and Kathleen seek to broaden and expand their reach and efforts in order to educate patients about pelvic health and to advocate for access to care, research into , and the development of treatment alternatives for these prevalent health conditions.

Have a Question?

Questions are great. Drop us a note and we promise to get back to you soon.

Thank you! Your question has been received.
We will respond to you promptly.
Oops! Something went wrong while submitting the form. Kindly try again.
If the problem persists, please drop us an email at contact@diagnoxhealth.com